In the present study we present a

2018-10-20

In the present study, we present a step-by-step strategy by which gene-corrected osteopetrotic iPSCs were used to generate hematopoietic progenitor SAG supplier able to give rise in vitro to functional osteoclasts, thus providing a proof of principle for an autologous cell therapy approach to treat

We previously discovered that ATM

2018-10-20

We previously discovered that ATM, in addition to serving many roles in cell-cycle regulation and DNA damage response, also functions as a key epigenetic regulator in neurons, likely underlying the ataxic symptoms as well as neurodegeneration. ATM indirectly regulates nuclear-cytoplasmic shuttling o

The AGM explant culture is

2018-10-20

The AGM explant culture is known to increase HSC activity. Whether the increase in AGM explant HSCs is due to the expansion and shift in BMP-activation status of existing HSCs, or the new generation of HSCs (non-BMP-activated), or both, remains unclear. Secondary transplantations of GFP+ and GFP− BM

br Results br Discussion The adult kidney has a low

2018-10-20

Results Discussion The adult kidney has a low rate of homeostatic cell cycling; yet, following injury, even one severe enough to cause total renal failure, widespread cell proliferation and functional recovery can occur. The mechanisms responsible for generation of new kidney cesium chloride

br Introduction Cardiac morphogenesis results

2018-10-20

Introduction Cardiac morphogenesis results from the specification, differentiation, and migration of spatially and temporally distinct sets of cardiac precursor RGDfK that give rise to the mature cardiac tissue. The first multipotent cardiogenic cells originate from the mesoderm formed at early

Male hypogonadism is characterized by the low production of

2018-10-20

Male hypogonadism is characterized by the low production of testosterone, which is associated with typical symptoms including mood disturbance, sexual dysfunction, decreased muscle mass and strength, and decreased bone mineral density (Howell et al., 2000). Hypogonadism affects approximately 30% of

Hello world!

2018-07-29