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As found in the previous
2019-05-10

As found in the previous study, miR-101 was significantly downregulated in CCA tumors compared with adjacent non-tumor tissues and this was supported by work from another group. This publication also found that miR-101 hepatic levels were decreased in CCA tumors compared with adjacent non-tumor tiss
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Maharaj K Bhan s accompanying Comment correctly identifies t
2019-05-10

Maharaj K Bhan\'s accompanying Comment correctly identifies that the main need is to obtain estimates on cause-specific mortality that are specific to each district. In particular, improved understanding is needed of how three causes, which account for 80% of neonatal deaths (birth asphyxia or traum
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Stigma and discrimination experienced by sex
2019-05-10

Stigma and discrimination experienced by sex workers, injection drug users, and men who have sex with men is tough to tackle. Responses need to be tailored to very different circumstances and require interventions on several levels: policy, societal, health system, and individual. There is no magic
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De acuerdo con los planteamientos anteriores pensemos en la
2019-05-10

De acuerdo con los planteamientos anteriores pensemos en la propuesta que se obtendría desde la obra de Villoro respecto reductase enzyme la situación política para un miembro perteneciente a una comunidad indígena, en tanto que además de pertenecer a ella se reconozca como ciudadano del Estado-naci
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The goals are set the
2019-05-10

The goals are set; the targets laid out. The fighting is over. In just over a week\'s time, heads of state worldwide will commit to the , with its 17 Sustainable Development Goals (SDGs) and 169 associated targets. Country representatives will resolve to do everything from ending poverty and hunger
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Although high and variable frequencies of sickle
2019-05-10

Although high and variable frequencies of sickle cell trait in different ethnic groups in Uganda have been reported previously, those data were from around 70 years ago and were based on small sample sizes. Thus, the findings of Ndeezi and colleagues provide a contemporary overview that is nationall
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br Methods br Results br Discussion br
2019-05-09

Methods Results Discussion Conclusions Conflict of interest statement Introduction The origin of a nonsustained ventricular tachycardia (NSVT) can usually be estimated with the 12-lead electrocardiogram (ECG) [1–3]; however, anatomical abnormalities sometimes make it difficult to c
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For HL most previous studies
2019-05-09

For HL, most previous studies have shown a correlation between decreasing survival rates for patients with HL with decreasing SES, although several studies found no or a varied association between survival outcomes in patients with HL with decreasing SES. The differences in these findings may be att
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Two studies are ongoing that promise to be
2019-05-09

Two studies are ongoing that promise to be paramount in the prescription of dexamethasone in the prophylaxis of pain flare. NCIC CTG is currently investigating the use of 8mg dexamethasone daily on the day of treatment and four days post-treatment versus placebo of the same duration (NCT01248585) [1
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Along the same line there is no information in
2019-05-09

Along the same line, there is no information in the literature on the optimal RT schedule in such cases. Doses ranging from 40 to 45Gy should be adequate and we chose to give 2Gy daily. This schedule was based on clinical and radiological evolution of the patient. RT limits natural evolution of the
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Introduction Schwannoma is a benign tumor of neuroectodermal
2019-05-09

Introduction Schwannoma is a benign tumor of neuroectodermal derivation that originates from Schwann arginase inhibitors which cover the peripheral nerves [3]. Approximately 25–40% of all schwannomas occur in the head and neck. These tumors most commonly arise in the soft tissues of the head and n
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br Update on the diagnosis of
2019-05-09

Update on the diagnosis of ERS ERS is generally diagnosed in patients who display ER in the inferior and/or lateral leads presenting with aborted cardiac arrest, documented VF, or polymorphic VT. Consistent with the recent consensus report on ERP [24], ER is recognized if (1) there is an end QRS
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The study by Wan Ling
2019-05-09

The study by Wan Ling Wong and colleagues examines the overall prevalence of age-related macular degeneration. In agreement with previous studies, Wong and colleagues have projected that 196 million people will be affected by age-related macular degeneration in 2020, increasing to 288 million by 204
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Premature deaths of women have profound
2019-05-09

Premature deaths of women have profound effects on families, societies, and economies, regardless of the age at which they occur and whatever the cause, including an—often preventable—NCD or injury later in life. Families, especially if female-headed, are driven into poverty through catastrophic hea
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In addition to inducing IKs dysfunction
2019-05-09

In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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