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The clinical presentation of patients with CIED pocket infec
2019-04-17
The clinical presentation of patients with CIED pocket infection and those with endovascular infection can vary, but once the diagnosis is made, the management is similar and involves removal of all hardware along with antibiotic therapy [2,7,8,15]. Conservative managements with Asiatic acid therap
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Bone marrow resident Macs Osteomacs are located
2019-04-17
Bone marrow resident Macs (Osteomacs) are located in canopy-like structures in endosteal and periosteal surfaces, above osteoblasts [6]; osteoclasts result from the fusion of several myeloid osteoclast precursors [7]. Osteomacs constitute approximately 17% of the bone marrow bortezomib sigma and the
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br Future perspectives Identification of LOX as a modulator
2019-04-17
Future perspectives Identification of LOX as a modulator of the ECM to form pre-metastatic niches and subsequently bone metastasis arose as we were investigating the hypoxia tumour secretome using existing patient cohort data and cutting edge proteomics. Although condoned by some researchers as “
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Furthermore the difference in the mean
2019-04-17
Furthermore, the difference in the mean S–A interval between HB capture and non-capture in the 4 patients with conduction pattern 2 or 3 was only 20±4ms (range, 16–27ms), and was shorter than the HV interval after ablation in 3 patients (75%). By contrast, in patients with strictly AV nodal retrogra
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Pero todo cambia despu s del exilio en Francia
2019-04-17
Pero todo cambia después del exilio en Francia; son los presuntos “bárbaros” los únicos que parecen ser capaces de una auténtica revolución: dirá Bilbao con admiración que ellos fueron los que en 1848 hicieron glycogen synthase kinase las “naciones de Europa […] estremecerse como bajo las plantas de
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Introduction Benign tumours of the bone consist of
2019-04-16
Introduction Benign tumours of the bone consist of a wide variety of different neoplasms. These tumours vary in terms of incidence, clinical presentation and require a diverse array of therapeutic options. The incidence of benign bone tumours is debated due to their often asymptomatic presentation
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Adipose tissue represents an alternative source of MSC like
2019-04-16
Adipose tissue represents an alternative source of MSC-like cells, avoiding the problems of pain, morbidity and low cell number associated with bone marrow harvest [17]. In plastic and reconstructive surgery, adipose tissue-derived stromal tizanidine hcl (ADSCs) may be used to increase in situ surv
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br Discovery of S PR
2019-04-16
Discovery of S1PR2 as a CBA sensor in the liver Early studies reported that activation of the ERK1/2 and AKT signaling pathways by CBAs was PTX-sensitive, suggesting a role for a Gαi-linked GPCR. To identify which GPCR activates the ERK1/2 and AKT signaling pathways, the cDNAs encoding more than
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br IntroduccI n Entre los a
2019-04-16
IntroduccIón Entre los años 1990 y 2013 se han aplicado en Chile once tipos de evaluaciones estandarizadas: las nacionales sImce, paa, psu e internacionales perce, tImss, cIved, pIsa y pIsa +, serce, Iccs, terce. Los resultados han sido, indefectiblemente, los mismos: siempre les va mal purchase
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Una de las teor as m
2019-04-16
Una de las teorías más destacadas sobre el género lo emparenta con el proyecto que llevaron CB-5083 cabo autores alemanes como Bertold Brecht o Walter Benjamin, quienes: Ana María Amar Sánchez, teórica que propone esta línea genealógica para explicar la creación testimonial del argentino Rodolfo Wa
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The p MAPK pathway activates AP to regulate transcription of
2019-04-16
The p38 MAPK pathway activates AP1 to regulate transcription of TNF-α [32,33]. Our results show that EC inhibits the expression of total c-Jun and p-c-Jun in the lungs of LPS-challenged mice. This finding suggests that EC may inhibit TNF-α production in the lungs via the p38 MAPK–AP1 signaling pathw
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Hereditary syndromes with increased risk for
2019-04-16
Hereditary syndromes with increased risk for gastric cancer include: 1) hereditary diffuse gastric cancer, 2) Lynch syndrome/hereditary non-polyposis colorectal cancer, 3) juvenile polyposis syndrome, 4) Peutz-Jeghers syndrome and 5) familial adenomatous polyposis. Hereditary diffuse gastric cancer
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br As the only methods available for
2019-04-16
As the only methods available for dual protection against pregnancy and sexually transmitted infections (STIs), male and female condoms have a vital role in sexual and reproductive health. Mags Beksinska and colleagues therefore are to be commended for their randomised crossover trial in this nop
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br The Ministerial Conference on in Asia and
2019-04-16
The Ministerial Conference on in Asia and the Pacific is taking place on Nov 24–28, 2014, in Bangkok, Thailand. In recognition of this and parallel plans from the UN Economic Commission for Africa for a Ministerial Conference on CRVS for African countries, to be held in Côte d\'Ivoire in February,
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LYL belongs to the basic helix
2019-04-15
LYL1 belongs to the basic helix-loop-helix (bHLH) transcription factor family, which plays important roles in a variety of developmental processes, including hematopoiesis [6]. The biological function of LYL1 is largely unknown, but its expression is restricted to hematopoietic cells, including myel
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