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br The last century has witnessed incredible progresses in
2018-11-14
The last century has witnessed incredible progresses in the control of infectious diseases. However, respiratory pathogens continue to threaten humans and cause serious public health and economic problems. Not only emerging pathogens but also viruses that have been known for a while continue to ca
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Senexin B In light of the preceding findings the
2018-11-14
In light of the preceding findings, the study by Darville and colleagues () is timely. They explored the therapeutic potential of more than 200 pharmacological agents, using neurons differentiated from iPS cells derived from ASD individuals heterozygous for null mutations. Darville et al. applied a
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br Conflicts of Interest br Author Contributions J Jian
2018-11-14
Conflicts of Interest Author Contributions J. Jian designed and performed experiments, collected and analyzed data, and wrote the paper. Q.Y. Tian, S. Zhao, H. Liu, and Y. Zhao performed experiments, collected and analyzed data. W. Chen, and G. Grunig established the chronic lung inflammation
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HEV may also contribute to various extrahepatic manifestatio
2018-11-14
HEV may also contribute to various extrahepatic manifestations, including pancreatitis, hematological disorders (thrombocytopenia and anemia), kidney disorders and neurological complications (Guillain-Barré syndrome and meningoencephalitis) (Singh and Gangappa, 2007; Thapa et al., 2009; Wedemeyer et
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br Augmenting B Memory Cell Function can Worsen MS Following
2018-11-14
Augmenting B Memory Cell Function can Worsen MS Following the apparent efficacy of CD20-depleting agents in controlling MS (Hauser et al., 2008; Kappos et al., 2011; Sorensen et al., 2014), alternative methods of depleting B cells have been developed. One approach was the use of CD19 depleting Cy
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br Methods br Results br
2018-11-14
Methods Results Discussion Differential methylation of specific CpG loci within the promoter region of ANRIL at the CDKN2A gene locus was predictive of measures of adiposity in four independent cohorts. In the UK SWS cohort (n=247), umbilical cord CDKN2A methylation was negatively associate
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Furthermore the specific role of these lipid subclasses on
2018-11-14
Furthermore, the specific role of these lipid subclasses on immune GM6001 is uncertain, and may vary according to lipid subtypes. Evidence suggests that depending on the subtype, some phosphatidylethanolamines have a pro-inflammatory role in activating macrophages (Guo et al., 2015), and appear to
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br Acknowledgments The data was collected with funding
2018-11-14
Acknowledgments The data was collected with funding from the East Carolina University Department of Economics. Ju-Chin Huang collaborated with the author on the survey design. Value of the data Materials and methods Specifications table Data, experimental design, materials and methods
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br Data The data in this data article
2018-11-14
Data The data in this data article has been gathered under a ‘Direct geothermal Avasimibe research and demonstration project’ run under the Sustainable Energy Pilot Demonstration (SEPD) program funded by the state government of Victoria, Australia. Under this project, around 20 buildings were se
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Successful performance on the transverse patterning
2018-11-13
Successful performance on the transverse patterning problem requires relational memory abilities, although there can be alternative strategies that support performance, such as in the rock-paper-scissors game or other semantic cues (Moses et al., 2008). The results of the present study show clearly
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This hypothesis was based on studies that suggest that lingu
2018-11-13
This order Tubastatin A HCl was based on studies that suggest that linguistic experience with “difficult to discriminate” durational cues alters ERP response to this feature (e.g., Nenonen et al., 2003; Tervaniemi et al., 2006) and that this enhanced processing extends to the non-speech domain (Kirm
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Several medications do appear to possess the
2018-11-13
Several medications do appear to possess the potential to induce or intensify RLS, including antiemetics, antipsychotics and antidepressants (tricyclic, serotonin reuptake inhibitors, selective noradrenergic–serotonergics) [9]. Amytriptiline chloride is a potent antidepressant with sedative and anti
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Perimenopausal and postmenopausal women usually sleep less t
2018-11-13
Perimenopausal and postmenopausal women usually sleep less; they have more insomnia and more necessity of medication to sleep than those premenopausal ones [8]. However, they usually do not talk to their doctors voluntarily and the health providers do not ask about aspects related to it. Insomnia, n
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br Fabrication and characterization of the device
2018-11-13
Fabrication and characterization of the device Results and discussion A picture of the fabricated system is reported in Fig. 5. The PDMS microfluidic network (the rectangular gray shape) lays in the upper right corner of the glass, the differential diode deposited on the glass substrate is hig
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To demonstrate the function of our portable
2018-11-13
To demonstrate the function of our portable transmittance reader, we collected data from our ALT assay over a wide range of ALT concentrations in human serum. For each concentration, we tracked the light transmission through four read zones in two assays. To run each ALT assay, we placed the assay i
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