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br If the quality of vibration suppression in the
2018-10-24
If the quality of vibration suppression in the beam proves unsatisfactory, it is necessary to return to identification experiments and additionally determine the subsequent rows of the eigenmode matrices. Next, it is necessary to recalculate the modal matrices according to formula (7) and use them
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Literacy is a fundamental resource highly correlated with
2018-10-24
Literacy is a fundamental resource highly correlated with educational attainment. Broadly, literacy has been defined as using printed and written information to function in society, to achieve one’s goals, and to develop one’s knowledge and potential. Literacy enables individuals to gain knowledge a
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The main goal of this paper is to develop and
2018-10-24
The main goal of this paper is to develop and use an ABM to evaluate different methods of targeting obesity interventions. Therefore, a model is needed that can, at minimum, incorporate three key factors determining the diffusion of intervention effects throughout a population: personal characterist
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TBs are still marginal as aforementioned However growing
2018-10-24
TBs are still marginal as aforementioned. However, growing participation in not-for-profit TBs, alternative currencies and other for-profit collaborative initiatives can change consumer habitus normalizing participation in C2C structures to satisfy their needs. As l-alanine learn and get socialized
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The genetic diversity and population structure of the specie
2018-10-23
The genetic diversity and population structure of the species have been elucidated by the use of two related methods, multilocus enzyme electrophoresis (MLEE) starting in the early 1980s and multilocus sequencing typing (MLST) at the end of the 1990s (Caugant et al., 1986a; Maiden et al., 1998). Bot
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ccr5 inhibitor Patritumab is a fully human
2018-10-23
Patritumab is a fully human anti-HER3 monoclonal antibody that demonstrates antitumor activity when used alone or with anti-EGFR inhibitors in preclinical cancer models (Freeman et al., 2009). Patritumab inhibits HRG-mediated HER3 signaling by binding to the extracellular domain of HER3 (thus preven
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The immunoregulatory and regenerative properties of MSCs mak
2018-10-23
The immunoregulatory and regenerative properties of MSCs make them ideal for use as therapeutic agents as they are uniquely positioned to suppress local inflammation and at the same time initiate tissue repair (). However, directing stem cell fate decisions towards a specific lineage is influenced
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In conclusion this first in human
2018-10-23
In conclusion, this first-in-human phase I study of VEDT was designed to establish the BED of VEDT for future investigations of the clinical activity of VEDT. VEDT is distinguished from other tocotrienols by its consistently superior anticancer activity in preclinical models. Although there are no a
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One major conserved DNA repair enzyme is the
2018-10-23
One major conserved DNA repair enzyme is the DNA2 helicase/nuclease (DNA2). Complete inactivation of either the helicase or nuclease activity of DNA2 in cells from a wide range of organisms, including yeast and humans, induces retinoic acid receptor arrest and cell death (Budd and Campbell, 1995; K
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Several conflicting large scale population based studies pub
2018-10-23
Several conflicting large-scale population-based studies published recently (e.g. (Lau et al., 2015; Moriya et al., 2015; Tsunoda et al., 2014)) indicated that p-gp inhibitors list moderate (or ‘non-alcoholic’) alcohol consumption either has a beneficial or detrimental association with prevalence o
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Hypothalamic hamartoma HH is a rare about
2018-10-23
Hypothalamic hamartoma (HH) is a rare (about 1:100,000) developmental, non-neoplastic malformation involving the small hypothalamic area located between the infundibular stalk and the mammillary bodies (). HH can be associated with a range of neurological and/or endocrinogical manifestations (). How
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Of note it is not known whether the
2018-10-23
Of note, it is not known whether the findings observed in the HOD model will translate to murine RBCs expressing other antigens, or to humans. Human studies investigating the role of RBC storage duration on alloimmunization and other adverse effects have reported varied outcomes (Dinardo et al., 201
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br Author contributions br Conflicts of Interest br Introduc
2018-10-23
Author contributions Conflicts of Interest Introduction With 15 million units transfused per year, red blood cell (RBC) transfusion is the most common procedure performed in United States hospitals (Pfuntner et al., 2013). Exposure to numerous foreign non-ABO RBC antigens during transfusion
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Despite its description over years ago by German
2018-10-23
Despite its description over 100years ago by German psychiatrist Alois Alzheimer, there has been little effective translation of insights on Alzheimer\'s disease (AD) pathobiology into effective treatments. As of 2015, roughly 50 million people globally — most over the age of 65years — have dementia
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The observational literature contains many investigations of
2018-10-23
The observational literature contains many investigations of racial differences in human TL, with findings that seem to contradict the association between shorter TL and stress. The majority of studies have found that U.S. blacks have longer telomeres than whites, despite on average lower socioecono
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